![]() Bhatt, MD, MPH, FACC, senior associate editor of ACC.org. Data reported by the international registry of acute aortic dissection (IRAD) in not sufficient to reflect clinical characteristics of acute aortic dissection. "These important data from IRAD nicely show how much progress has been made in the care of patients with aortic dissection," says Deepak L. Better diagnostic tools are needed to identify patients at risk and speed treatment in acute dissection. The investigators conclude that they expect endovascular, surgical and medical therapies to evolve and improve patient outcomes. Overall in-hospital mortality for Type B dissection has decreased from 10.2 percent to 7.4 percent, and five-year survival increased from 74 percent to 83.7 percent. ![]() For Type A dissection, overall in-hospital mortality has fallen from 26.2 percent to 16.3 percent, and five-year survival increased from 81.9 percent to 88.5 percent.įor Type B management, results show that endovascular therapy has increased from 19.5 percent to 31.2 percent, and surgery management has dropped from 15 percent to 6.1 percent. Of note, surgical management has increased for Type A dissection from 85 percent to 88.6 percent. The International Registry of Acute Aortic Dissection (IRAD), which is the largest single dataset on the subject, has sharp severe pain as the most common presenting complaint. CT scan remains the most common diagnostic imaging test. Results showed that hypertension, smoking and atherosclerosis are the most common risk factors for aortic dissection. Investigators compared diagnosis, treatment, in-hospital and five-year mortality. Gore & Associates, participating International Registry of Acute Aortic Dissection (IRAD) aortic centers of excellence, Medtronic, the Varbedian Aortic Research Fund, the Hewlett Foundation, the Mardigian Foundation, the University of Michigan Faculty Group Practice, Terumo, and. Eagle, MD, MACC, et al., looked at 9,000 patients enrolled in the International Registry of Acute Aortic Dissection (IRAD) at 55 centers in 13 countries from 1996-2019. Funding/Support: This research was generously supported by W.L. All rights reserved.In patients with acute aortic dissection, in-hospital mortality for Type A and Type B dissection has decreased over time, with an increase in five-year survival, according to results of the IRAD study presented March 18 at ACC.19 in New Orleans, LA. Our study shows differences in type, etiology, and presentation of blacks and whites with acute aortic dissection, yet similar mortality for these cohorts.Ĭopyright © 2013 Elsevier Inc. 110, odds ratio 0.704, 95% confidence interval 0.457-1.085) and at 3 years postdischarge, as evaluated by Kaplan-Meier survival analysis (22.0% vs 14.3%, P =. Mortality was similar in-hospital (14.3% vs 19.1%, P =. Hypotension/shock/tamponade was less common (7.6% vs 20.1%, P <.001), whereas acute kidney failure was more common (41.0% vs 21.7%, P <.001) in blacks. Presenting features were similar except for more abdominal pain (44.6% vs 30.6%, P <.001) and left ventricular hypertrophy on echocardiogram (44.2% vs 20.1%, P <.001) in blacks. 010), and prior aortic dissection repair (7.7% vs 12.8%, P =. The International Registry of Acute Aortic Dissections suggests that patients with an acute dissection. ![]() 029), iatrogenic dissection (0.5% vs 4.5%, P =. dissection of the abdominal aorta presented aortic. Conversely, they were less likely to have bicuspid aortic valve (1.8% vs 5.8%, P =. In 1996, the International Registry of Acute Aortic Dissection (IRAD. Type B acute aortic dissection was more frequent in the black cohort (52.4% vs 39.3%, P =. Hoping to overcome the small numbers of patients enrolled at single centers over decades, three investigators convened at the American College of Cardiology symposium in 1995 to discuss combining their individual efforts to create a multi-center registry of aortic dissection. ![]() We excluded patients of other racial descent. We evaluated black (n = 189, 14%) or white (n = 1165, 86%) patients (mean age 62.8 ± 15.3 years 36.4% women) enrolled in 13 US centers participating in the International Registry of Acute Aortic Dissection. Few data exist on race-related differences in acute aortic dissection patients. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |